Longitudinal measurements of RGC density <i>in vivo</i> by CSLO in Group-1 (ONT versus ONT fellow eyes) and Group-3 (sham ONT versus sham fellow eyes) animals.

<p>The density of CTB-labeled RGCs decreased in ONT eyes by 18%, 69%, 85% and 92% relative to baseline at follow-up weeks 1, 2, 3 and 4, respectively. RGC density significantly decreased at week-3 by 20% and decreased 19% by week-4. RGC density did not change significantly in sham or sham-fellow eyes. *Significant change from baseline assessed by two-way repeated measures ANOVA with Bonferroni post-hoc tests on raw values. Error bars indicate SEM.