Comparison of human EEG with model output in regime N2.

<p>Qualitative comparison of (a) human EEG data of sleep stage N2 from electrode Cz with (b) the isolated cortical module in regime N2 (region IV in the bifurcation diagram in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003923#pcbi-1003923-g002" target="_blank">Figure 2</a>). The traces illustrate the medium-amplitude background oscillations and the stereotypical shape of spontaneous KCs at the EEG level. It may or may not have an initial bump followed by a large negative peak and a pronounced positive overshoot. The model-KC is noise induced and represents a single relaxation cycle. An evoked KC in the noise-free case is shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003923#pcbi-1003923-g004" target="_blank">Figure 4a</a>. Model output is excitatory membrane voltage <i>V_e</i>, and both time series are z-scored (Parameters as in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003923#pcbi-1003923-t002" target="_blank">Table 2</a>).