Effect of Myd88 overexpression on the antiviral activity of poly(I:C).

<p>Japanese flounder were administered with PBS (control), pCN3, pCNMyd88, poly(I:C), or poly(I:C) in the presence pCNMyd88. The fish were then infected with megalocytivirus, and at different days (d) of infection, the amounts of virus in kidney (A) and spleen (B) were determined. Data are expressed as the mean ± SE (<i>N</i> = 3). <i>N</i>, the number of experimental repeat. *<i>P</i><0.05; **<i>P</i><0.01.