Cell migration distance of human gingival fibroblasts in the gel type and sponge type scaffolds.

<p>The migration distance of human gingival fibroblasts in gel type and sponge type scaffolds with and without platelet-derived growth factor-BB (PDGF) was measured and is presented as the mean migration distance from the scaffold border ± standard deviation in the region of interest that was 0.5 mm high and 1.5 mm wide. Area under the curve (AUC) analysis was performed from 1 to 14 days. (n = 6–7). Data was analyzed using analysis of variance (ANOVA) and Fisher's protected least significant difference (PLSD) post hoc test. Significance (*, #) was assigned at p<0.05. Colored pound sign (#) indicates the first time a difference to day 1 was observed for the group of the corresponding color. The PDGF containing sponge type scaffolds was different from the scaffolds alone from day 7 to day 14. The PDGF containing gel type scaffold was different from the gel type scaffold from day 4 to day 14.