Effect of CEACAM6 on MMP-9 activity, and cell migratory and invasive ability in GC cells.

<p>(A) The supernatant of GC cells was collected after 24 h. Then the MMP-9 activity was examined by gelatin zymography. (B) Relative MMP-9 expression in GC cells. (C, E) Transwell assay. Images show cells that had traveled through the micropore membrane with or without matrigel (200×). (D, F) Histograms showed the numbers of migrating cells and invading cells. The results are means of three independent experiments in the bar graphs. *<i>P</i><0.05, **<i>P</i><0.01.