Myocardial CCL21 and CCR7 mRNA and CCL21 protein expression in experimental LV pressure overload.

<p>Left ventricular expression of (<b>A</b>) CCL21 mRNA, (<b>B</b>) CCL21 protein levels and (C) CCR7 mRNA in mice with compensated (n = 7) and de-compensated (n = 7) hypertrophy three weeks after aortic banding, compared to sham operated mice (n = 7). mRNA levels were quantified by real-time RT-PCR and are presented relative to the gene expression of GAPDH. CCL21 protein levels were quantified by Western blotting. Data are mean±SEM. *p<0.05, **p<0.01 and ***p<0.001 vs. controls/sham.