<p>These mutations were below the detection threshold for other mutation calling algorithms used by TCGA. The ratio of reads supporting the mutations along with the variant allele frequencies are shown for both the DNA and RNA. Validation was done on four of the mutations, and the resulting validation DNA variant allele frequencies are shown.</p><p>RNA Rescue Mutations in Lung Adenocarcinoma not Detected by Other Methods in TCGA.</p
Identification of driver mutations in lung adenocarcinoma has led to development of targeted agents ...
<p>A) Using a cutoff of 1.5% variant allele percentage, 46 of the 47 mutations present in the tumor ...
Non-small cell lung cancers (NSCLC), in particular adenocarcinoma, are often mixed with normal cells...
<div><p>The detection of rare mutants using next generation sequencing has considerable potential fo...
The detection of rare mutants using next generation sequencing has considerable potential for diagno...
The detection of somatic single nucleotide variants is a crucial component to the characterization o...
We identify critical conserved and mutated genes through a theoretical model linking a gene’s fitnes...
<p>Detected mutations (including Missense point mutations/deletion/insertion) in 45 genes (737 loci)...
<p>Mutations (including Missense point mutations/deletion/insertion) frequencies in 45 genes (737 lo...
The detection of somatic single nucleotide variants is a crucial component to the characterization o...
Identification of driver mutations in lung adenocarcinoma has led to development of targeted agents ...
<p>Artificial mutations were spiked into the tumor DNA and RNA BAM files of a breast cancer patient ...
<div><p>The detection of somatic single nucleotide variants is a crucial component to the characteri...
In recent years, we have seen a dramatic improvement in our ability to detect nucleotide changes in ...
Exome sequence capture and massively parallel sequencing can be combined to achieve inexpensive and ...
Identification of driver mutations in lung adenocarcinoma has led to development of targeted agents ...
<p>A) Using a cutoff of 1.5% variant allele percentage, 46 of the 47 mutations present in the tumor ...
Non-small cell lung cancers (NSCLC), in particular adenocarcinoma, are often mixed with normal cells...
<div><p>The detection of rare mutants using next generation sequencing has considerable potential fo...
The detection of rare mutants using next generation sequencing has considerable potential for diagno...
The detection of somatic single nucleotide variants is a crucial component to the characterization o...
We identify critical conserved and mutated genes through a theoretical model linking a gene’s fitnes...
<p>Detected mutations (including Missense point mutations/deletion/insertion) in 45 genes (737 loci)...
<p>Mutations (including Missense point mutations/deletion/insertion) frequencies in 45 genes (737 lo...
The detection of somatic single nucleotide variants is a crucial component to the characterization o...
Identification of driver mutations in lung adenocarcinoma has led to development of targeted agents ...
<p>Artificial mutations were spiked into the tumor DNA and RNA BAM files of a breast cancer patient ...
<div><p>The detection of somatic single nucleotide variants is a crucial component to the characteri...
In recent years, we have seen a dramatic improvement in our ability to detect nucleotide changes in ...
Exome sequence capture and massively parallel sequencing can be combined to achieve inexpensive and ...
Identification of driver mutations in lung adenocarcinoma has led to development of targeted agents ...
<p>A) Using a cutoff of 1.5% variant allele percentage, 46 of the 47 mutations present in the tumor ...
Non-small cell lung cancers (NSCLC), in particular adenocarcinoma, are often mixed with normal cells...