Telomere length according to age in patients with bone marrow failure or idiopathic pulmonary fibrosis measured by Southern blot, flow-FISH and qPCR.

<p>Lines represent the 1st, 10th, 50th, 90th, 99th percentiles of telomere length of healthy controls (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113747#pone.0113747.s001" target="_blank">Figure S1</a></b>). (<b>A</b>) Telomere length measurement by Southern blot was used to define patients with dyskeratosis congenita or BMF/IPF with telomerase mutation who had very short telomeres (<1st percentile; represented by red dots), patients with short telomeres (<10th percentile; represented by black dots) and patients with normal telomeres (above 10th percentile; circles). (<b>B</b>) Telomere length measurement by flow-FISH of patients with very short, short and normal telomeres defined by Southern blot. (<b>C</b>) Telomere length measurement by qPCR of patients with very short, short and normal telomeres defined by Southern blot.