Kinetics of injected fluorescently labeled IgA in a fluorescence molecular tomography system.

<p>A fluorescence molecular tomography system (FMT) is capable of resolving size and concentration of fluorochromes in deep tissue <i>in vivo</i>. Fluorescein-labeled IgA samples from gddY and Balb/c mice were injected into nude mice and monitored from 10 min to 24 h postinjection by FMT. After 2 h, IgA signals in the liver and bladder were found in a similar manner in both the groups of nude mice. However, IgA signals in the kidneys clearly differed between them. Mice injected with gddY IgA showed strong signals in the kidneys, with a peak at 4 h.