Transmission electron microscopy images of <i>in vitro</i> expanded ADSCs.

<p>ADSCs from cancer patients at passage 2 (A) and passage 4 (C) show cytoplasms enriched with organelles and large nucleus (N) with loosely packed chromatin. A detail of the ADSC from passage 2 (B) shows organelle enrichment, rough endoplasmic reticulum (arrows) and large Golgi cisternae (asterisk) with some lipid drops (Li). ADSCs at passage 4 (C) show prominent nuclear invaginations (arrows) and enlarged nucleoli (Nu). At low magnification also shows abundant electro-dense organelles. At a higher magnification abundant rough endoplasmic reticulum cisternae, lipid drops (Li) and abundant membranous structures or autophagosomes are appreciated (D). Scale bar 10 µm (A–C); 1 µm (B–D).