ß-adrenergic signaling prolongs APD90 in miR KO ventricular cardiomyocytes.

<p>Representative APs of control (black traces) and KO cells without (blue traces) and in presence of Isoproterenol (ISO; 1 µM, red traces) (A). Statistics of APD90 in miR WT and KO cells without and with ISO (B). Point graphs of APD90 of individual cells prior and after Isoproterenol application underscores the different response of control and miRNA KO cells (C). Percentage of increase of APD90 in miR control and KO cells (D).