PDI inhibition attenuates NP-mediated generation of cGMP in vivo.

<p>Mice were given ANP with or without PDI inhibitors. Blood samples were collected, cGMP levels assessed. Data are expressed as mean<u>+</u>SEM (n = 6 mice). * p value ≤0.05 vs ANP with addition of RL90 antibody, and ** p value ≤0.001 with addition of Bacitracin.