Effects of melatonin on folate contents in maternal sera and embryos.

<p>In LPS group, pregnant mice were i.p. injected with LPS (25 µg/kg) daily from GD8 to GD12. In LPS+melatonin (MT) group, pregnant mice were orally administered with melatonin (50 mg/kg) 1 h before each LPS injection. In control group, pregnant mice were i.p. injected with NS daily from GD8 to GD12. In melatonin alone group, pregnant mice were orally administered with melatonin (50 mg/kg) 1 h before each NS injection. All pregnant mice were sacrificed 12 h after the last LPS injection. Folate contents in maternal sera and embryos were measured. Data were presented as means ± S.E.M. of twelve samples from twelve different pregnant mice. ^**<i>P</i><0.01, ^*<i>P</i><0.05.