Effects of melatonin on the expression of frα and pcft in mouse placentas.

<p>In LPS group, pregnant mice were i.p. injected with LPS (25 µg/kg) on GD10. In LPS+melatonin (MT) group, pregnant mice were orally administered with melatonin (50 mg/kg) 1 h before LPS injection. In control group, pregnant mice were i.p. injected with NS on GD10. In melatonin alone group, pregnant mice were orally administered with melatonin (50 mg/kg) 1 h before NS injection. All pregnant mice were sacrificed 12 h after LPS injection. Placental frα and pcft mRNAs were measured using real-time RT-PCR. (A) frα; (B) pcft. Data were presented as means ± S.E.M. of six samples from six different pregnant mice. ^**<i>P</i><0.01, ^*<i>P</i><0.05.