Effect of NMDA and AMPA/kainate receptor blockade on myenteric neuron count after I/R damage.

<p>Concentration-response curves represent the effect of -AP5 (A-C) and CNQX (D–F) on the number/mm² of myenteric neurons obtained from rat small intestine after inducing chemical ischemia (B, E) and after reperfusion (C, F) with respect to values obtained in normal metabolic conditions (A, D). Percentage variation of neuron number/mm² is plotted against log molar concentrations of -AP5 (A-C) and CNQX (D–F). Each point represents the mean of 4 experiments. Vertical bars indicate S.E.M.