Nod1 also dampens <i>S.</i> Typhimurium Δ<i>msbB</i>-induced colitis.
- Anne-Kathrin Claes (665736)
- Natalie Steck (665737)
- Dorothee Schultz (665738)
- Ulrich Zähringer (37778)
- Simone Lipinski (665739)
- Philip Rosenstiel (68103)
- Kaoru Geddes (272724)
- Dana J. Philpott (168628)
- Holger Heine (213291)
- Guntram A. Grassl (665740)
Publication date
November 2014
DOIAbstract
<p>Streptomycin-pretreated C57Bl/6, <i>Nod1<sup>−/−</sup></i> and DKO mice were orally infected with <i>S.</i> Typhimurium Δ<i>msbB</i> for 2 days. (A) <i>S.</i> Typhimurium colonization of ileum, cecum and colon. Dashed line: limit of detection; cfu: colony forming units. (B) Pathology scores of infected ceca. Statistical analysis: 1way ANOVA with Bonferroni's multiple comparison post-test. * <i>p</i><0.05; ** <i>p</i><0.01. (C) H&E staining of infected cecum sections. Original magnification 200×; scale bars = 100 µm.</p
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