Varied TF expression levels in macrophages derived from different sources in wild-type (WT), HTF and low TF mice in response to <i>M.tb</i> and LPS stimulation.

<p>Macrophages (∼0.5×10⁵ cells) were either stimulated with live <i>M.tb</i> (10 CFU/cell) or 10 µg/ml of gamma-irradiated <i>M.tb</i> (<i>γ-M.tb</i>) for overnight in antibiotic free RPMI complete medium. Macrophages were also stimulated with LPS (1 µg/ml) as a positive control for 6 h. At the end of the treatment, TF activity was measured in FX activation assay. * denotes significantly different from unstimulated controls. (* p<0.05; ** p≤0.001; *** p<0.0001) as obtained by Students t-test. Data are mean ± SEM (n = 6–17).