Neurotropin (NTP) suppresses interleukin-1β (IL-1β) and tumor necrosis factor-α (TNFα)-induced nuclear translocation of the nuclear factor-κB (NF-κB).

<p>Wild type (WT) primary hepatocytes were pretreated with 0.2 NU/mL NTP for 1 hour followed by the treatment with 2 ng/mL TNFα or IL-1β for 15 minutes. Immunofluorescence for NF-κBp65 is shown. Representative staining for p65 (A; Green, p65; Blue, Nucleus) and quantification (B) are shown. Scale bar, 40 µm. Data represent the mean±SEM of 8 high power fields (x200).