[NiFe]-hydrogenases catalyze the cleavage of molecular hydrogen into protons and electrons and represent promising tools for H<sub>2</sub>-based technologies such as biofuel cells. However, many aspects of these enzymes remain to be understood, in particular how the catalytic center can be protected from irreversible inactivation by O<sub>2</sub>. In this work, we combined homology modeling, all-atom molecular dynamics, and coarse-grain Brownian dynamics simulations to investigate and compare the dynamic and mechanical properties of two [NiFe]-hydrogenases: the soluble O<sub>2</sub>-sensitive enzyme from <i>Desulfovibrio fructosovorans</i>, and the O<sub>2</sub>-tolerant membrane-bound hydrogenase from <i>Aquifex aeolicus</i>. We investigat...
Hydrogenases are promising candidates for the catalytic production of green energy by means of biolo...
International audienceFeFe hydrogenases are the most efficient H$_2$-producing enzymes. However, ina...
[FeFe] hydrogenases, metalloenzymes catalyzing proton/dihydrogeninterconversion, have attracted inte...
International audience[NiFe]-hydrogenases catalyse the cleavage of molecular hydrogen into protons a...
[NiFe] hydrogenases are enzymes that catalyze the splitting of molecular hydrogen according to the r...
Hydrogenase enzymes are natural biocatalysts that might be harnessed to reduce the cost of hydrogen ...
Hydrogenases are efficient biocatalysts for H2 production and oxidation with various potential biote...
AbstractHydrogenases catalyze the reversible oxidation of molecular hydrogen (H2), but little is kno...
Designing O<sub>2</sub>-tolerant hydrogenases is a major challenge in applying [Fe–Fe]H<sub>2</sub>...
The H<sub>2</sub> production potential of [FeFe]-hydrogenase, a hydrogen-producing enzyme from green...
AbstractPossible proton transport pathways in Clostridium pasteurianum (CpI) [FeFe]-hydrogenase were...
© 2016 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. FeFe hydrogenases...
To better understand the proton transport through the H<sub>2</sub> production catalysts, the [FeFe]...
[FeFe] hydrogenase enzymes can reversibly catalyze the conversion of protons into molecular hydrogen...
The high turnover rates of [FeFe]-hydrogenases under mild conditions and at low overpotentials provi...
Hydrogenases are promising candidates for the catalytic production of green energy by means of biolo...
International audienceFeFe hydrogenases are the most efficient H$_2$-producing enzymes. However, ina...
[FeFe] hydrogenases, metalloenzymes catalyzing proton/dihydrogeninterconversion, have attracted inte...
International audience[NiFe]-hydrogenases catalyse the cleavage of molecular hydrogen into protons a...
[NiFe] hydrogenases are enzymes that catalyze the splitting of molecular hydrogen according to the r...
Hydrogenase enzymes are natural biocatalysts that might be harnessed to reduce the cost of hydrogen ...
Hydrogenases are efficient biocatalysts for H2 production and oxidation with various potential biote...
AbstractHydrogenases catalyze the reversible oxidation of molecular hydrogen (H2), but little is kno...
Designing O<sub>2</sub>-tolerant hydrogenases is a major challenge in applying [Fe–Fe]H<sub>2</sub>...
The H<sub>2</sub> production potential of [FeFe]-hydrogenase, a hydrogen-producing enzyme from green...
AbstractPossible proton transport pathways in Clostridium pasteurianum (CpI) [FeFe]-hydrogenase were...
© 2016 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. FeFe hydrogenases...
To better understand the proton transport through the H<sub>2</sub> production catalysts, the [FeFe]...
[FeFe] hydrogenase enzymes can reversibly catalyze the conversion of protons into molecular hydrogen...
The high turnover rates of [FeFe]-hydrogenases under mild conditions and at low overpotentials provi...
Hydrogenases are promising candidates for the catalytic production of green energy by means of biolo...
International audienceFeFe hydrogenases are the most efficient H$_2$-producing enzymes. However, ina...
[FeFe] hydrogenases, metalloenzymes catalyzing proton/dihydrogeninterconversion, have attracted inte...