<i>tsp-17 (gt1681)</i> enhances the neurodegeneration phenotype of <i>cat-2</i>-overexpressing lines, and <i>cat-2</i> overexpression protects against 6-OHDA toxicity.

<p><b>A</b>. <i>cat-2</i> induced neurodegeneration. Analysis of <i>cat-2</i>-overexpressing stains UA57 <i>baIn4 [pdat-1::gfp pdat-1::cat-2]</i> and TG2402 <i>baIn4[pdat-1::gfp pdat-1::cat-2]; tsp-17(gt1681)</i>. Error bars represent standard deviation. Asterisks represent statistical difference between <i>cat-2::gfp</i> adults on days 5 and 7 (**p<0.005). <b>B</b>. <i>cat-2</i> overexpression suppresses 6-OHDA-induced neurotoxicity. Experiments were done in triplicate and the average is shown. Data presented is from scoring the extent of neurodegeneration 72 h post 6-OHDA intoxication.