Levels of Aβ species in brain samples of mice treated with JZL184 or vehicle.
- Larisa V. Lysenko (669533)
- Jeesun Kim (231518)
- Cassandra Henry (669534)
- Anna Tyrtyshnaia (669535)
- Rebecca A. Kohnz (669536)
- Francisco Madamba (669537)
- Gabriel M. Simon (131638)
- Natalia E. Kleschevnikova (669538)
- Daniel K. Nomura (198023)
- R . Alan B. Ezekowitz (669539)
- Alexander M. Kleschevnikov (669540)
Publication date
December 2014
DOIAbstract
<p>A: Levels of Aβ40 were significantly increased in the vehicle-treated Ts65Dn vs. 2N mice. JZL184-treatment reduced the levels of Aβ40 in both Ts65Dn and 2N samples. B: Levels of Aβ42 were also greater in Ts65Dn vs 2N samples and were reduced by the JZL184-treatment.</p
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