Treg/Th17 relationship during candidiasis.

<p>Tregs promote Th17 responses as well as acquire Th17 characteristics during disseminated infection. However, Treg/Th17 responses are associated with pathogenicity in this form of candidiasis. Conversely, Treg enhancement of Th17 responses during OPC is protective. Tregs suppress Th17 responses during gastrointestinal candidiasis, leading to decreased <i>C. albicans</i> colonization. Whether Tregs impact Th17 responses during vaginal and cutaneous candidiasis and the resulting outcome of disease remains to be determined.