The NKX2.1 protein levels were significantly lower, (A), in the SGC-7901 and higher in the MPC-803 and HGC-27 cell lines than in the normal gastric cell line GES.

<p>(<b>B</b>) The NKX2.1 expression was significantly higher in the NKX2.1 transfected SGC-7901 cells and lower in the siNKX2.1 transfected MPC-803/HGC-27 cells than controls. (<b>C-E</b>) The MTS assay showed that NKX2.1 suppressed the proliferation of the over-expressed SGC-7901 and accelerated the proliferation of the down-regulated MPC-803/HGC-27 cells, * P < 0.05.