<p>All genes with a discovery nominal P<1×10<sup>−3</sup> that also replicated in a dataset of a <i>different</i> disease (see main text). The table mirrors <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113684#pone-0113684-t002" target="_blank">Table 2</a>, with the only difference being whether replication is in the same disease (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0113684#pone-0113684-t002" target="_blank">Table 2</a>) or a different one (this table). Cases in which the same association is replicated in multiple datasets span several rows.</p><p>Gene-based associations replicating in other diseases.</p
MOTIVATION: Gene networks have become a central tool in the analysis of genomic data but are widely ...
<p>Disease-associated repeat sequence can include microsatellites (1–4 bp unit), minisatellites (6–6...
Association replication studies have a poor track record and, even when successful, often claim asso...
<p>All genes with a discovery nominal P<1×10<sup>−3</sup> (in <i>Discovery dataset</i>) that also re...
The genotypes of individuals in replicate genetic association studies have some level of correlation...
The genotypes of individuals in replicate genetic association studies have some level of correlation...
With the advent of genome-wide association (GWA) studies, researchers are hoping that reliable genet...
<p>The table shows the replicated associations of the SNP rs207650 in <i>TOMM40/APOE</i> in the repl...
<p>(A) We calculated the functional relatedness of the interaction partners (blue circles) of a gene...
Background: Searching for associations between genetic variants and complex diseases has been a very...
Replication within existing epigenome-wide association studies that examined the same condition in t...
Replication has become the gold standard for assessing statistical results from genome-wide associat...
<p>Comparing with duplicated non-disease genes (ND) of similar duplication age (represented by branc...
Background: Previous studies of network properties of human disease genes have mainly focused on mon...
<p>Three curated gene sets were tested for association with disease risk. Displayed are datasets for...
MOTIVATION: Gene networks have become a central tool in the analysis of genomic data but are widely ...
<p>Disease-associated repeat sequence can include microsatellites (1–4 bp unit), minisatellites (6–6...
Association replication studies have a poor track record and, even when successful, often claim asso...
<p>All genes with a discovery nominal P<1×10<sup>−3</sup> (in <i>Discovery dataset</i>) that also re...
The genotypes of individuals in replicate genetic association studies have some level of correlation...
The genotypes of individuals in replicate genetic association studies have some level of correlation...
With the advent of genome-wide association (GWA) studies, researchers are hoping that reliable genet...
<p>The table shows the replicated associations of the SNP rs207650 in <i>TOMM40/APOE</i> in the repl...
<p>(A) We calculated the functional relatedness of the interaction partners (blue circles) of a gene...
Background: Searching for associations between genetic variants and complex diseases has been a very...
Replication within existing epigenome-wide association studies that examined the same condition in t...
Replication has become the gold standard for assessing statistical results from genome-wide associat...
<p>Comparing with duplicated non-disease genes (ND) of similar duplication age (represented by branc...
Background: Previous studies of network properties of human disease genes have mainly focused on mon...
<p>Three curated gene sets were tested for association with disease risk. Displayed are datasets for...
MOTIVATION: Gene networks have become a central tool in the analysis of genomic data but are widely ...
<p>Disease-associated repeat sequence can include microsatellites (1–4 bp unit), minisatellites (6–6...
Association replication studies have a poor track record and, even when successful, often claim asso...