<p>Tumor sizes at the end of the experiment were 122.33+/−105.86 mm<sup>2</sup> (mean +/− SD) in the control group, 76.73+/−36.09 mm<sup>2</sup> in tumors treated with SGK-1 inhibitor, 94.52+/−75.92 mm<sup>2</sup> in the Cisplatin group, and 25.76+/−14.89 mm<sup>2</sup> with combination of local SGK-1 inhibition and systemic cisplatin. Black arrows indicate timing of systemic cisplatin-, and blue arrows timing of SGK-1 Inhibitor application. Repeated measures ANOVA for growth rates (<b>B</b>). Newman-Keuls Multiple Comparison Test for growth rates; df = degrees of freedom, Sig. = Significance; Diff. = Difference, q = studentized range value, ** = p<0.001; *** = p<0.0001 (<b>C</b>).</p
International audienceIn early phase clinical trials of cytotoxic drugs in oncology, the efficacy is...
International audienceIn early phase clinical trials of cytotoxic drugs in oncology, the efficacy is...
International audienceIn early phase clinical trials of cytotoxic drugs in oncology, the efficacy is...
<p>After 11 days of tumor inoculation, tumors were touchable. Then mice were randomly regrouped (n =...
<p>Tumors measured in two dimensions with calipers every 2 days prior to administration of treatment...
<p>The majority of patients randomized to sunitinib had no evidence of acceleration in the rate of g...
Modeling the natural growth of tumors is of value for evaluation of tumor progression and optimizati...
(A) Changes in tumor volume as a function of time after implantation. Tumor growth curves are shown ...
<p>The majority of patients randomized to sunitinib had no evidence of acceleration in the rate of g...
<p>The volume ratio of the tumor was obtained from the initial volume (V<sub>0</sub>) at the onset o...
<p>A) Normalized tumour growth curves. A delayed tumour growth in all treatment conditions was noted...
<p>GraphPad Prism Software was used to perform a two-way ANOVA of tumor growth data after treatment ...
<p>FEMX-1 xenografts were treated with lexatumumab (L) (10 mg/kg, twice a week, i.v. injection), IgG...
BACKGROUND: Treatment effect is categorised into four classes by RECIST based on the evolution of th...
<p>SNU-16 stomach tumor-bearing mice that were analyzed for imaging signals after the first and seco...
International audienceIn early phase clinical trials of cytotoxic drugs in oncology, the efficacy is...
International audienceIn early phase clinical trials of cytotoxic drugs in oncology, the efficacy is...
International audienceIn early phase clinical trials of cytotoxic drugs in oncology, the efficacy is...
<p>After 11 days of tumor inoculation, tumors were touchable. Then mice were randomly regrouped (n =...
<p>Tumors measured in two dimensions with calipers every 2 days prior to administration of treatment...
<p>The majority of patients randomized to sunitinib had no evidence of acceleration in the rate of g...
Modeling the natural growth of tumors is of value for evaluation of tumor progression and optimizati...
(A) Changes in tumor volume as a function of time after implantation. Tumor growth curves are shown ...
<p>The majority of patients randomized to sunitinib had no evidence of acceleration in the rate of g...
<p>The volume ratio of the tumor was obtained from the initial volume (V<sub>0</sub>) at the onset o...
<p>A) Normalized tumour growth curves. A delayed tumour growth in all treatment conditions was noted...
<p>GraphPad Prism Software was used to perform a two-way ANOVA of tumor growth data after treatment ...
<p>FEMX-1 xenografts were treated with lexatumumab (L) (10 mg/kg, twice a week, i.v. injection), IgG...
BACKGROUND: Treatment effect is categorised into four classes by RECIST based on the evolution of th...
<p>SNU-16 stomach tumor-bearing mice that were analyzed for imaging signals after the first and seco...
International audienceIn early phase clinical trials of cytotoxic drugs in oncology, the efficacy is...
International audienceIn early phase clinical trials of cytotoxic drugs in oncology, the efficacy is...
International audienceIn early phase clinical trials of cytotoxic drugs in oncology, the efficacy is...