<p>Immunized and control mice were infected with 4.0×10<sup>6</sup> cfu (4.14× LD<sub>50</sub>) of the ATCC 19606 strain. (A) Twelve hours post-infection spleen, kidney and lung bacterial loads were determined (n = 8 mice/IB010 vaccine group; n = 7 mice/control group; n = 6 mice/ATC 19606 vaccine group). Data points represent bacterial loads from individual mice, and horizontal lines represent median values from groups of mice. * p<0.05 compared to control mice. (B) Vaccinated and control mice were infected with 4.0×10<sup>6</sup> cfu (4.14× LD<sub>50</sub>) of the ATCC 19606 strain and survival was monitored for seven days. (n = 7 mice/IB010 vaccine group; n = 8 mice/control group); n = 8 mice/ATC 19606 vaccine group) * p<0.05 compared to ...
<p>Twelve groups of BALB/c mice (n = 3–9) were infected by the i.v. route with four different strain...
<p>Survival after infection with 1.3 x 10<sup>9</sup><i>E</i>. <i>faecalis</i>. P = 0.0096 EF 12030 ...
<p>T-cell depleted mice fail to restrain growth of secondary challenge bacteria from 72 h p.i. Bacte...
<p>Mice (n = 8) were immunized with the octa-valent vaccine containing IsaA-His<sub>6</sub>, LytM-Hi...
<p>Calculated CFU are shown against time for saline controls [closed squares] and in mice previously...
<p>Live vaccine but not killed vaccine controls bacterial loads following secondary challenge. Bacte...
<p>C57BL/6 mice (A, B, C) and C3H/FeJ mice (D, E, F) were infected with individual KZN strains by ae...
<p>(A) Mice were infected i.p. with 10<sup>6</sup> CFUs, at indicated times CFU/spleen and spleen we...
<p>Mice were inoculated intratracheally using a Microsprayer device to aerosolize the indicated numb...
<p>(A) The bacterial load in the lungs of mice was measured at 24 hr after i.n. infection with 100 L...
<p>Stat1flfl, Stat1−/− and LysMCreStat1flfl mice were infected for 72 h with 1×10∧5 Lm i.p and bacte...
<p>Mice were inoculated intratracheally using a Microsprayer device to aerosolize the indicated numb...
<p><b><i>A</i></b> and <b><i>B</i></b>, Eight mice per group were infected with the wild-type and th...
<p>Bacterial loads in the <b>(A)</b> Peyer’s patches (PP), <b>(B)</b> mesenteric lymph nodes (MLN), ...
<p>(A) CIs for the Δ<i>lgt</i> strain versus the wild-type strain in mouse models of septicaemia at ...
<p>Twelve groups of BALB/c mice (n = 3–9) were infected by the i.v. route with four different strain...
<p>Survival after infection with 1.3 x 10<sup>9</sup><i>E</i>. <i>faecalis</i>. P = 0.0096 EF 12030 ...
<p>T-cell depleted mice fail to restrain growth of secondary challenge bacteria from 72 h p.i. Bacte...
<p>Mice (n = 8) were immunized with the octa-valent vaccine containing IsaA-His<sub>6</sub>, LytM-Hi...
<p>Calculated CFU are shown against time for saline controls [closed squares] and in mice previously...
<p>Live vaccine but not killed vaccine controls bacterial loads following secondary challenge. Bacte...
<p>C57BL/6 mice (A, B, C) and C3H/FeJ mice (D, E, F) were infected with individual KZN strains by ae...
<p>(A) Mice were infected i.p. with 10<sup>6</sup> CFUs, at indicated times CFU/spleen and spleen we...
<p>Mice were inoculated intratracheally using a Microsprayer device to aerosolize the indicated numb...
<p>(A) The bacterial load in the lungs of mice was measured at 24 hr after i.n. infection with 100 L...
<p>Stat1flfl, Stat1−/− and LysMCreStat1flfl mice were infected for 72 h with 1×10∧5 Lm i.p and bacte...
<p>Mice were inoculated intratracheally using a Microsprayer device to aerosolize the indicated numb...
<p><b><i>A</i></b> and <b><i>B</i></b>, Eight mice per group were infected with the wild-type and th...
<p>Bacterial loads in the <b>(A)</b> Peyer’s patches (PP), <b>(B)</b> mesenteric lymph nodes (MLN), ...
<p>(A) CIs for the Δ<i>lgt</i> strain versus the wild-type strain in mouse models of septicaemia at ...
<p>Twelve groups of BALB/c mice (n = 3–9) were infected by the i.v. route with four different strain...
<p>Survival after infection with 1.3 x 10<sup>9</sup><i>E</i>. <i>faecalis</i>. P = 0.0096 EF 12030 ...
<p>T-cell depleted mice fail to restrain growth of secondary challenge bacteria from 72 h p.i. Bacte...