1<p>Manually handled, gel expelled in trash, n = 2.</p>2<p>Unopened applicator, removed from foil packet only, n = 2.</p>3<p>BLD = Below level of detection.</p><p>Quantitation of Residual Tenofovir (TFV) on Gel Applicators.</p
Aims: An efficient therapeutic drug or antiviral agent to treat Covid-19 is still not available. But...
<p>Hair TFV concentrations for each subject are shown for each dosing period. Each line represents d...
(A) ARV drug and TFV-DP levels in vaginal biopsies collected on Day 7 within 30 min of pod-IVR remov...
ARV drug levels in CVF fall off rapidly following IVR removal (grey arrow) but are quantifiable for ...
ARV drug levels in CVF fall off rapidly following IVR removal (grey arrow) but are quantifiable for ...
<p>The <i>in vitr</i>o release data show the release profile of tenofovir from the gel; the slope of...
ARV drug levels in CVFs fall off rapidly following IVR removal (grey arrows) but are quantifiable fo...
<p>Each data point represents mean ± SE of 5 measurements, except for the control (0%) and 0.45% dat...
Trials of a vaginal Tenofovir gel for pre-exposure prophylaxis (PrEP) for HIV have given conflicting...
Trials of a vaginal Tenofovir gel for pre-exposure prophylaxis (PrEP) for HIV have given conflicting...
<p>A mass balance computation calculated the difference between the initial amount of Tenofovir in t...
§<p>Predicted compartment dose concentrations to suppress 50, 90 and 95% of HIV infection interpolat...
(A) ARV drug and TFV-DP levels in vaginal biopsies collected on Day 7 within 30 min of pod-IVR remov...
<p>Standard conditions for gel, epithelial and stromal thicknesses. These are at different times in ...
<div><p><b>time in tissue and the top fluid compartment in the Transwell assay</b>. </p> <p>Transwel...
Aims: An efficient therapeutic drug or antiviral agent to treat Covid-19 is still not available. But...
<p>Hair TFV concentrations for each subject are shown for each dosing period. Each line represents d...
(A) ARV drug and TFV-DP levels in vaginal biopsies collected on Day 7 within 30 min of pod-IVR remov...
ARV drug levels in CVF fall off rapidly following IVR removal (grey arrow) but are quantifiable for ...
ARV drug levels in CVF fall off rapidly following IVR removal (grey arrow) but are quantifiable for ...
<p>The <i>in vitr</i>o release data show the release profile of tenofovir from the gel; the slope of...
ARV drug levels in CVFs fall off rapidly following IVR removal (grey arrows) but are quantifiable fo...
<p>Each data point represents mean ± SE of 5 measurements, except for the control (0%) and 0.45% dat...
Trials of a vaginal Tenofovir gel for pre-exposure prophylaxis (PrEP) for HIV have given conflicting...
Trials of a vaginal Tenofovir gel for pre-exposure prophylaxis (PrEP) for HIV have given conflicting...
<p>A mass balance computation calculated the difference between the initial amount of Tenofovir in t...
§<p>Predicted compartment dose concentrations to suppress 50, 90 and 95% of HIV infection interpolat...
(A) ARV drug and TFV-DP levels in vaginal biopsies collected on Day 7 within 30 min of pod-IVR remov...
<p>Standard conditions for gel, epithelial and stromal thicknesses. These are at different times in ...
<div><p><b>time in tissue and the top fluid compartment in the Transwell assay</b>. </p> <p>Transwel...
Aims: An efficient therapeutic drug or antiviral agent to treat Covid-19 is still not available. But...
<p>Hair TFV concentrations for each subject are shown for each dosing period. Each line represents d...
(A) ARV drug and TFV-DP levels in vaginal biopsies collected on Day 7 within 30 min of pod-IVR remov...