<p>Validation of differentially expressed miR-146a in <i>ex vivo</i> central cornea vs. limbus, <b>A</b>; and in normal vs diabetic limbus, <b>B</b>; by Q-PCR. Bars represent SEM of pooled values (n = 5) ** p<0.001 and * p<0.05 by paired two-tailed t test.</p
<p>The boxplots for miR-148a-3p (<b>a</b>); miR-204-5p (<b>b</b>); miR-223-3p (<b>c</b>); miR-375 (<...
<p>The expression of 4 miRNAs (miR-192, miR-194, miR-21, and miR-200a) was evaluated using qRT-PCR i...
(A-C) qRT-PCR expression levels of various mRNAs (shown on x axis) measured in WT (black) or miR-146...
<p><i>In </i><i>situ</i> hybridization with locked nucleic acid (LNA) modified probes was performed ...
<p><b>A.</b> Normal LEC transfected with miR-146 increased, whereas its inhibitor decreased both Fri...
<p>MiR-146a inhibitor treatment in diabetic organ-cultured corneas led to increased expression of si...
<p>All 9 transcripts were preferentially expressed in the limbus and minimally expressed in the corn...
Limbal epithelial stem cells (LESC) residing at the corneal periphery are largely responsible for ma...
<p>MiR-146a mature form expression was analyzed in nerve (A, B) and skin (C, D) specimens by real-ti...
<p>(<b>A</b>) Quantitative real-time PCR of miR-146a in control cortex (n = 6; autopsy), FCD type II...
PurposeMiR-146a upregulated in limbus vs. central cornea and in diabetic vs. non-diabetic limbus has...
Limbal epithelial stem cells (LESC) residing at the corneal periphery are largely responsible for ma...
<p>ARBP used as a reference gene with pluronic treated samples serving as baseline controls. RNA ext...
<p>Blue bars represent the results from microarray, while red bars indicate the results from qRT-PCR...
<p>(A, B, and C) Results of quantitative PCR (qPCR) analyses of miR-21, miR-204, and let-7e levels f...
<p>The boxplots for miR-148a-3p (<b>a</b>); miR-204-5p (<b>b</b>); miR-223-3p (<b>c</b>); miR-375 (<...
<p>The expression of 4 miRNAs (miR-192, miR-194, miR-21, and miR-200a) was evaluated using qRT-PCR i...
(A-C) qRT-PCR expression levels of various mRNAs (shown on x axis) measured in WT (black) or miR-146...
<p><i>In </i><i>situ</i> hybridization with locked nucleic acid (LNA) modified probes was performed ...
<p><b>A.</b> Normal LEC transfected with miR-146 increased, whereas its inhibitor decreased both Fri...
<p>MiR-146a inhibitor treatment in diabetic organ-cultured corneas led to increased expression of si...
<p>All 9 transcripts were preferentially expressed in the limbus and minimally expressed in the corn...
Limbal epithelial stem cells (LESC) residing at the corneal periphery are largely responsible for ma...
<p>MiR-146a mature form expression was analyzed in nerve (A, B) and skin (C, D) specimens by real-ti...
<p>(<b>A</b>) Quantitative real-time PCR of miR-146a in control cortex (n = 6; autopsy), FCD type II...
PurposeMiR-146a upregulated in limbus vs. central cornea and in diabetic vs. non-diabetic limbus has...
Limbal epithelial stem cells (LESC) residing at the corneal periphery are largely responsible for ma...
<p>ARBP used as a reference gene with pluronic treated samples serving as baseline controls. RNA ext...
<p>Blue bars represent the results from microarray, while red bars indicate the results from qRT-PCR...
<p>(A, B, and C) Results of quantitative PCR (qPCR) analyses of miR-21, miR-204, and let-7e levels f...
<p>The boxplots for miR-148a-3p (<b>a</b>); miR-204-5p (<b>b</b>); miR-223-3p (<b>c</b>); miR-375 (<...
<p>The expression of 4 miRNAs (miR-192, miR-194, miR-21, and miR-200a) was evaluated using qRT-PCR i...
(A-C) qRT-PCR expression levels of various mRNAs (shown on x axis) measured in WT (black) or miR-146...
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