1<p>Chemical Abstracts Registration Number;</p>2<p>Cytotoxic activity measured in the US National Cancer Institute (NCI) 60 human tumour cell line anticancer drug screen <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0114904#pone.0114904-Shoemaker1" target="_blank">[55]</a>, GI<sub>50</sub> corresponds to the concentration of the drug resulting in a 50% growth inhibition.</p><p>Compounds selected from screening with etoposide pharmacophores – biological results.</p
<p>The 95% confidence intervals (CI) for each experiment were plotted against the geometric mean (bl...
<p><strong>Dataset: Recognizing molecular mechanisms of antitumor compounds from cytostatic activity...
<p>A: Hierarchical clustering of inhibitory profiles of all kinase drugs in a panel of more than 300...
<p>Results are expressed as percentage of the fluorescence intensity measured in cells treated with ...
Drug development consists of many sequential and parallel steps; failure in one of the steps can lea...
Cancer is one of the major life threatening diseases worldwide. The available anticancer drugs have ...
<p>Cells were treated with increasing concentrations of the substances for 24 h and cell viability w...
Etoposide is a chemotherapy drug that is used in the treatment of various types of cancer, including...
Metabolism studies of the antitumor drug etoposide show the formation of metabolites in the lactone ...
<p>Asexual stage 10 µM inhibition data was obtained from the Collaborative Drug Discovery Database (...
<p>SYBR Green I assay results for the Johns Hopkins Clinical Compound Library version 1.3 of FDA app...
<p>NCI-H69V treated with 200 µM Etoposide showed significantly increased chemoresistance in comparis...
BACKGROUND: The European NCI compounds programme, a joint initiative of the EORTC Research Branch, C...
The following reference genotoxic agents were tested in the in vitro micronucleus test, at Novartis,...
<p>Results are expressed as mean ± SD of at least three independent experiments. IC<sub>50</sub> val...
<p>The 95% confidence intervals (CI) for each experiment were plotted against the geometric mean (bl...
<p><strong>Dataset: Recognizing molecular mechanisms of antitumor compounds from cytostatic activity...
<p>A: Hierarchical clustering of inhibitory profiles of all kinase drugs in a panel of more than 300...
<p>Results are expressed as percentage of the fluorescence intensity measured in cells treated with ...
Drug development consists of many sequential and parallel steps; failure in one of the steps can lea...
Cancer is one of the major life threatening diseases worldwide. The available anticancer drugs have ...
<p>Cells were treated with increasing concentrations of the substances for 24 h and cell viability w...
Etoposide is a chemotherapy drug that is used in the treatment of various types of cancer, including...
Metabolism studies of the antitumor drug etoposide show the formation of metabolites in the lactone ...
<p>Asexual stage 10 µM inhibition data was obtained from the Collaborative Drug Discovery Database (...
<p>SYBR Green I assay results for the Johns Hopkins Clinical Compound Library version 1.3 of FDA app...
<p>NCI-H69V treated with 200 µM Etoposide showed significantly increased chemoresistance in comparis...
BACKGROUND: The European NCI compounds programme, a joint initiative of the EORTC Research Branch, C...
The following reference genotoxic agents were tested in the in vitro micronucleus test, at Novartis,...
<p>Results are expressed as mean ± SD of at least three independent experiments. IC<sub>50</sub> val...
<p>The 95% confidence intervals (CI) for each experiment were plotted against the geometric mean (bl...
<p><strong>Dataset: Recognizing molecular mechanisms of antitumor compounds from cytostatic activity...
<p>A: Hierarchical clustering of inhibitory profiles of all kinase drugs in a panel of more than 300...