Neuronal activation during pure tone exposure within a primary auditory cortex column.

<p>Representative peri-stimulus time histograms (PSTHs) acquired during exposure to 25-ms (A) and 50-ms (B) pure tones across twelve cortical depth locations in primary auditory cortex. Diagram on right-hand side illustrates microelectrode array orientation with respect to cortical depth and PSTH displays. Note that irrespective of acoustic signal duration, PSTH profiles remain similar across cortical depth with a prominent single onset response. Representative acoustic signal type and duration are presented in gray. Location of recording track and corresponding receptive fields are illustrated in <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0114550#pone-0114550-g007" target="_blank">Fig. 7</a></b>.