1<p>WCE, whole cell exctract.</p>2<p>glyco, partially purified glycosome fraction.</p>3<p>Mean ± SEM of n experiments (mU/mg of protein).</p>4<p>+gluc: cells cultured in SDM79 containing 10 mM glucose.</p>5<p>−gluc: cells cultured in glucose-depleted SDM79GluFree.</p><p>NADPH-dependent 3-hydroxyacyl-CoA dehydrogenase activity in WT and Δ<i>tfeα1</i>/Δ<i>tfeα1</i> cells.</p
<p>NAD, NADH, NADP and NADPH in each cell line were quantitatively determined at 24, 48 and 72 hours...
<p>Green boxes represent metabolite pools that were quantified experimentally while white ones were ...
Abstract Background The glycosylation of recombinant proteins can be altered by a range of parameter...
Various producer cell lines used for large scale production of biopharmaceuticals like monoclonal an...
Animal cell culture processes are needed for the production of monoclonal antibodies, recombinant pr...
Mammalian cells are widely used for the production of a variety of biopharmaceuticals, such as monoc...
Lactate and ammonia are the most important waste products of central carbon metabolism in mammalian ...
<p>(<b>A</b>) The glucose and pyruvate concentrations, and aconitase activity in wild type (HD1A) an...
<p>Solid lines represent the paths analyzed in this Fig and in Fig 4; blue triangles indicate the si...
<p>(<b>A</b>) Enzymatic activities (n = 3), transcript levels (n = 9), and protein levels (n = 3) fo...
The effect of different carbon sources on Δ5 desaturation activity in Minimal Deviation Hepatoma 728...
<p>(A) Overview of cellular ketone body metabolism. Upon starvation, FAs are metabolized to ketone b...
<p>NG, constant normal glucose (5 mM); HG, constant high glucose (22 mM); and N/HG, 5 mM alternating...
<p>(A) Compared with the NC group, glucose consumption was significantly increased in the WT group a...
<p>Overnight cultured primary hepatocytes from WT and <i>Glmp</i><sup><i>gt/gt</i></sup> mice were i...
<p>NAD, NADH, NADP and NADPH in each cell line were quantitatively determined at 24, 48 and 72 hours...
<p>Green boxes represent metabolite pools that were quantified experimentally while white ones were ...
Abstract Background The glycosylation of recombinant proteins can be altered by a range of parameter...
Various producer cell lines used for large scale production of biopharmaceuticals like monoclonal an...
Animal cell culture processes are needed for the production of monoclonal antibodies, recombinant pr...
Mammalian cells are widely used for the production of a variety of biopharmaceuticals, such as monoc...
Lactate and ammonia are the most important waste products of central carbon metabolism in mammalian ...
<p>(<b>A</b>) The glucose and pyruvate concentrations, and aconitase activity in wild type (HD1A) an...
<p>Solid lines represent the paths analyzed in this Fig and in Fig 4; blue triangles indicate the si...
<p>(<b>A</b>) Enzymatic activities (n = 3), transcript levels (n = 9), and protein levels (n = 3) fo...
The effect of different carbon sources on Δ5 desaturation activity in Minimal Deviation Hepatoma 728...
<p>(A) Overview of cellular ketone body metabolism. Upon starvation, FAs are metabolized to ketone b...
<p>NG, constant normal glucose (5 mM); HG, constant high glucose (22 mM); and N/HG, 5 mM alternating...
<p>(A) Compared with the NC group, glucose consumption was significantly increased in the WT group a...
<p>Overnight cultured primary hepatocytes from WT and <i>Glmp</i><sup><i>gt/gt</i></sup> mice were i...
<p>NAD, NADH, NADP and NADPH in each cell line were quantitatively determined at 24, 48 and 72 hours...
<p>Green boxes represent metabolite pools that were quantified experimentally while white ones were ...
Abstract Background The glycosylation of recombinant proteins can be altered by a range of parameter...