Active site of pyranose dehydrogenase (PDH; PDB code 4H7U) from <i>Agaricus meleagris</i> with bound sugar (SUG; here β-d-glucose).

<p>To transfer the sugar coordinates from pyranose 2-oxidase (P2O) from <i>Trametes multicolor</i> into PDH, the X-ray structures of both enzymes were first superimposed. The β-d-glucose coordinates from the P2O structures with PDB codes (A) 3PL8 – termed pose A – or (B) 2IGO – termed pose B – were grafted into PDH. Atom-coloring scheme: carbon (beige, protein; yellow, FAD; white, ligand), nitrogen (blue), and oxygen (red). The figure was generated using PyMOL (<a href="http://www.pymol.org/" target="_blank">http://www.pymol.org/</a>).