HGF gene-modified ADSCs migrate to damaged tissue sites.

<p>(A) TUNEL staining of liver sections from the control group and liver sections from the RILD group 2 days post-irradiation. Arrows indicate hepatocytes that are positive for TUNEL staining. (B) Quantification of TUNEL-positive cells. Five fields were randomly selected from each specimen, and the number of TUNEL-positive cells was determined (×400). (C) HE stain of liver specimens obtained from the control group and from the RILD group 60 days after irradiation. Arrow indicates vacuolar degeneration in liver. (D) ADSCs expressing GFP were detected in rat liver 7, 14 and 30 days after transplantation (100×). Arrows indicate cells positive for GFP staining. (E) HGF was detected by ELISA in rat liver 2 weeks after transplantation. *<i>p</i><0.05.