Experimental set-up.

<p><b>Day 0</b>: Right nephrectomy in both groups. Subsequent biopsy of the upper pole of the residual kidney in the Bx group and sham biopsy of the residual kidney in the control group. <b>Day 7</b>: Biopsy of the lower kidney pole in the Bx group and second sham biopsy in the control group. <b>Day 42</b>: Animals were sacrificed and kidneys were removed for histology. Body weight, blood pressure, proteinuria and serum creatinine were measured before operations on day 0 and day 42 in both groups (*).