Behavioral analysis of <i>Mto1</i> mutant mice using a modified holeboard.

<p><i>Mto1</i>−/−mice show increased horizontal locomotor activity (A) as well as increased mean velocity (B) as compared to controls. Anxiety-related behavior measured via the time on board (C) and group contact (D) was also significantly changed; object exploration was increased (E) and acoustic startle response decreased (F), *p<0.05; **p<0.01.