Experiment 2: Time-course of locomotor activity in DAT/5-HT1B KO mice, short habituation sessions.

<p>Time-course of saline and cocaine-induced locomotor activity in DAT/5-HT1B KO mice, represented separately for each genotype. Cocaine increased locomotion in all DAT +/+ and DAT +/− genotypes (p<0.01), and reduced locomotion in all DAT −/− genotypes (p<0.01) except DAT −/−5-HT1B, which was confirmed by individual ANOVA comparing saline and cocaine locomotion for each genotype. Data are represented as mean ± SEM.