Pulmonary viral clearance after vaccination with lipopeptide or split virus vaccines.

<p>Mice were immunised by the i.n. (red), s.c. (blue) or i.m. (green) route with incremental doses of either lipopeptide (A) or split virus (B) on one occasion. One month post-immunisation, mice were challenged by the i.n. route with 10^4.5 pfu of virus. The lungs were removed 5 days later and pulmonary viral titre determined by plaque formation. Symbols represent the geometric mean for the group (n = 5) and error bars indicate the standard error.