<p><i>Top</i>: Sequence of the hTERT core promoter with the positions of mutations observed in melanomas shown in red. <i>Bottom</i>: Previously proposed structure of the hTERT core promoter (5). Adapted with permission from (5).</p
AbstractActivation of telomerase by human papillomavirus 16 (HPV16) E6 is a critical step for cell i...
In previous studies we reported that the expression of HLA-DR on melanoma cell lines was differentia...
<p>(<b>a</b>) Bars, left axis: Number of mutations occurring in the established recurrent CTTCCG-rel...
Mutations occur at four specific sites in the hTERT promoter in >75% of glioblastomas and melanomas,...
<div><p>Mutations occur at four specific sites in the hTERT promoter in >75% of glioblastomas and me...
<p>(A) Chromatogram of a part of hTERT core promoter region, no mutation was detected in any of the ...
Transcriptional reactivation of hTERT is the limiting step in tumorigenesis. While mutations in hTER...
Activation of human telomerase reverse transcriptase (hTERT) is necessary for limitless replication ...
© 2015 American Association for Cancer Research. With the recent discovery of recurrent mutations i...
<p>Whole genome sequencing data from 38 melanomas were analyzed for individual recurrently mutated b...
Sequencing of whole tumor genomes holds the promise of revealing functional somatic regulatory mutat...
Background Melanoma is a heterogeneous group of diseases with distinct sets of genetic changes. Recu...
<p><b>A:</b> Schematic representation of the Sp1 binding sites in the promoters under study. Gray el...
(a) Highly recurrent somatic mutations (individual genomic bases) aggregate near annotated transcrip...
AIM: To determine the mutation status of human telomerase reverse transcriptase gene (TERT) promoter...
AbstractActivation of telomerase by human papillomavirus 16 (HPV16) E6 is a critical step for cell i...
In previous studies we reported that the expression of HLA-DR on melanoma cell lines was differentia...
<p>(<b>a</b>) Bars, left axis: Number of mutations occurring in the established recurrent CTTCCG-rel...
Mutations occur at four specific sites in the hTERT promoter in >75% of glioblastomas and melanomas,...
<div><p>Mutations occur at four specific sites in the hTERT promoter in >75% of glioblastomas and me...
<p>(A) Chromatogram of a part of hTERT core promoter region, no mutation was detected in any of the ...
Transcriptional reactivation of hTERT is the limiting step in tumorigenesis. While mutations in hTER...
Activation of human telomerase reverse transcriptase (hTERT) is necessary for limitless replication ...
© 2015 American Association for Cancer Research. With the recent discovery of recurrent mutations i...
<p>Whole genome sequencing data from 38 melanomas were analyzed for individual recurrently mutated b...
Sequencing of whole tumor genomes holds the promise of revealing functional somatic regulatory mutat...
Background Melanoma is a heterogeneous group of diseases with distinct sets of genetic changes. Recu...
<p><b>A:</b> Schematic representation of the Sp1 binding sites in the promoters under study. Gray el...
(a) Highly recurrent somatic mutations (individual genomic bases) aggregate near annotated transcrip...
AIM: To determine the mutation status of human telomerase reverse transcriptase gene (TERT) promoter...
AbstractActivation of telomerase by human papillomavirus 16 (HPV16) E6 is a critical step for cell i...
In previous studies we reported that the expression of HLA-DR on melanoma cell lines was differentia...
<p>(<b>a</b>) Bars, left axis: Number of mutations occurring in the established recurrent CTTCCG-rel...