Proteomic array detection of stem cell associated proteins in pooled aliquots from 9 HR-HPV+ve cervical samples from women with CIN3 (A) and 9 HPV –ve samples with normal cytology (B); (C & D) map and key for array spots; (E) average pixel density ranked by ratio of pooled CIN3:normal samples for each protein on the array; (F) sox2, TP63 and HCG mRNAs are upregulated in HPV+ve cervical samples with severe dyskaryosis compared to HPV–ve samples with normal morphology (* = p<0.05, ** p<0.01, Mann Whitney test).

<p>Proteomic array detection of stem cell associated proteins in pooled aliquots from 9 HR-HPV+ve cervical samples from women with CIN3 (A) and 9 HPV –ve samples with normal cytology (B); (C & D) map and key for array spots; (E) average pixel density ranked by ratio of pooled CIN3:normal samples for each protein on the array; (F) sox2, TP63 and HCG mRNAs are upregulated in HPV+ve cervical samples with severe dyskaryosis compared to HPV–ve samples with normal morphology (* = p<0.05, ** p<0.01, Mann Whitney test).