Cytotoxicity effect of thymoquinone.

<p>(A) Chemical structure of thymoquinone. (B) The cell viability after 24 h of treatment. Each point is the mean ± S.D. of three independent experiments. (C) Normal phase contrast inverted micrograph for 0, 24, 48, and 72 h. In control, most of the cells exhibited normal morphology while some cells showed cytoplasmic protrusions (24 h); clearly blebbing and apoptosis were observed (48 h); most of the cell exhibited growth inhibition and apoptosis (72 h). White arrows: membrane blebbing; yellow arrows: Apoptosis.