<p>N27 cells were transfected with mock control, catalytically inactive mutant MMP3 (MutMMP3), or actMMP3 vector for 24, 48, or 72 h. Mitochondrial ROS levels were determined by the MitoSox staining (A) and MitoSox level (B) was quantified at 24 h after transfected with MutMMP3 and ActMMP3. Cells expressing GFP (green) represent vector-transduced cells. Scale bar = 10 µm (C) MMP-3 enzyme activity assay on lysates of N27 cells transfected with MutMMP3 and ActMMP3 for 48 or 72 h. (D) Representative photomicrographs of Western blots against Nox1 on lysates of N27 cells transfected with MutMMP3 and ActMMP3 for 48 h. Densitometric analysis of the western blots results normalized against β-actin and expressed as % induction compared with MutMMP3...
<p>STAT3 activation of MMP3 has not been previously reported. Therefore, we sought to detect whether...
<p>A) Analysis of MMP3 expression by qRT-PCR in BM-MSCs (black bars), HUCPVCs (white bars) or AT-MSC...
<p>Fibroblasts isolated from the hearts of p27-deficient mice were lentivirally transduced with an e...
<p>(A) Mitochondrial ROS generation was measured using the MitoSox staining in N27 dopaminergic cell...
<p>(A) A representative RT-PCR performed on various Nox subunits from RNA preparation of N27 cells t...
<p>(A) Representive photographs of Western blots for tubulin, histone H3, Tim 23 in the total lysate...
<p>(A) Representative photomicrographs of Nox1 -immunoreactivity in the SN sections. AAV2 particles ...
<p>(A) Detection of mitochondrial ROS in live cells. Live MSCs were treated with Ara-C (100 mM for 2...
In the present study we investigated the interplay between matrix metalloproteinase 3 (MMP3) and NAD...
In the present study we investigated the interplay between matrix metalloproteinase 3 (MMP3) and NAD...
<p>(<b>A</b>) HONE-1 cells were transfected with a vector plasmid (Vec) or a Zta-expressing plasmid,...
<p>A) Equivalent numbers of LP9 and HM cells were deprived of serum for 72 hr, then incubated in med...
<p>PEMs and RAW264.7 cells were infected with MHV-3 (MOI = 1) <i>in vitro</i>, the NOX-derived ROS (...
<p>(A) Increase of membrane-associated NOX activity in cells with mitochondrial respiratory defects ...
<p>Schematic diagram of the interplay between MMP3 and Nox1 in the process of dopaminergic neuronal ...
<p>STAT3 activation of MMP3 has not been previously reported. Therefore, we sought to detect whether...
<p>A) Analysis of MMP3 expression by qRT-PCR in BM-MSCs (black bars), HUCPVCs (white bars) or AT-MSC...
<p>Fibroblasts isolated from the hearts of p27-deficient mice were lentivirally transduced with an e...
<p>(A) Mitochondrial ROS generation was measured using the MitoSox staining in N27 dopaminergic cell...
<p>(A) A representative RT-PCR performed on various Nox subunits from RNA preparation of N27 cells t...
<p>(A) Representive photographs of Western blots for tubulin, histone H3, Tim 23 in the total lysate...
<p>(A) Representative photomicrographs of Nox1 -immunoreactivity in the SN sections. AAV2 particles ...
<p>(A) Detection of mitochondrial ROS in live cells. Live MSCs were treated with Ara-C (100 mM for 2...
In the present study we investigated the interplay between matrix metalloproteinase 3 (MMP3) and NAD...
In the present study we investigated the interplay between matrix metalloproteinase 3 (MMP3) and NAD...
<p>(<b>A</b>) HONE-1 cells were transfected with a vector plasmid (Vec) or a Zta-expressing plasmid,...
<p>A) Equivalent numbers of LP9 and HM cells were deprived of serum for 72 hr, then incubated in med...
<p>PEMs and RAW264.7 cells were infected with MHV-3 (MOI = 1) <i>in vitro</i>, the NOX-derived ROS (...
<p>(A) Increase of membrane-associated NOX activity in cells with mitochondrial respiratory defects ...
<p>Schematic diagram of the interplay between MMP3 and Nox1 in the process of dopaminergic neuronal ...
<p>STAT3 activation of MMP3 has not been previously reported. Therefore, we sought to detect whether...
<p>A) Analysis of MMP3 expression by qRT-PCR in BM-MSCs (black bars), HUCPVCs (white bars) or AT-MSC...
<p>Fibroblasts isolated from the hearts of p27-deficient mice were lentivirally transduced with an e...