ARAP3 is dispensable in Prx1-expressing bone marrow niche cells for steady-state hematopoiesis.

<p>(A) BM cells from <i>f/f</i> control and <i>f/−;Prx1</i> CKO mice were quantified for the percentage of cells in various HSPC populations. Bars show mean ±SEM. n = 3. (B) LSK cells from <i>f/f</i> and <i>f/−;Prx1</i> donor mice were transplanted into irradiated recipient mice. Peripheral blood of individually reconstituted mice was assessed by flow cytometry at 12 weeks post-transplant for the distribution of cell lineages within donor-derived cells (bars, left Y-axis) and the percentage of total donor leukocytes (black diamonds, right Y-axis). P-values determined by Student's t-test.