FTIR spectra of <i>L. monocytogenes</i> re-isolated from challenged mice.

<p>(A) Average FTIR spectra derived from 129/Sv (dotted), Tyk2−/− (dashed) and C57BL/6 (solid) isolates are shown from the whole spectral range (B) Subtraction spectra were generated from second derivative, vector-normalized, average FTIR spectra of the three different mouse genotypes. Spectra from C57BL/6 mice were subtracted from 129/Sv isolates (black), spectra from C57BL/6 mice were subtracted from Tyk2−/− (red) and spectra from Tyk2−/− were subtracted from 129/Sv isolates (blue). Most pronounced differences were observed in the spectral range of 1700–1500 cm⁻¹ (protein region) and can be assigned to amide I (1670–1625 cm⁻¹) and amide II (1560–1530 cm⁻¹).