<p>The numbers represented the concentration of P95H plasmid diluted with wild-type plasmid. The maximal sensitivity was 10%.</p
Somatic mutations of the spliceosome machinery have been recently identified by whole genome analysi...
High Resolution Melting Analysis (HRMA) is becoming the preferred method for mutation detection. How...
Conventional mutation analysis requires a separation step and include single-strand conformational p...
<p>A) Depicts different degrees of chimerism (amount red colored cells) that could occur due to cust...
<p>(A) Schematic illustration of the principle of HRMA. A small region of the genome that includes a...
<p>A) Depicts compound mutation (different colored cells) in a chimeric animal that could occur due ...
<p>A: normalized melting curves; B: normalized difference curves. HRMA identified mutated R882H with...
<p>Grey lines represented wild-type <i>SRSF2</i>; green and blue lines were validated as P95H mutati...
<p>HRM can efficiently identify single gene mutation containing F1 from pooled guide injections.</p
Detecting NPM1 gene mutations using the E-ice-COLD-PCR assay and generating the data into HRM differ...
<p>A&B) General depiction of HRM analysis. A homozygous wild-type sample (double blue lines in A) wi...
a<p>[Number of drug-resistant isolates with mutations]/[number of drug-resistant isolates with mutat...
Wild-type (pcDNA3.1-EGFRwild-type) and mutant (pcDNA3.1-EGFRL858R/T790M) EGFR expression plasmids we...
<p><i>BRAF</i> mutation status determined by HRM using DNA treated with BSA or purified using the Nu...
<p>Melting curves (A) and difference plots (B) of wild-type (blue) and serial dilutions of a <i>CALR...
Somatic mutations of the spliceosome machinery have been recently identified by whole genome analysi...
High Resolution Melting Analysis (HRMA) is becoming the preferred method for mutation detection. How...
Conventional mutation analysis requires a separation step and include single-strand conformational p...
<p>A) Depicts different degrees of chimerism (amount red colored cells) that could occur due to cust...
<p>(A) Schematic illustration of the principle of HRMA. A small region of the genome that includes a...
<p>A) Depicts compound mutation (different colored cells) in a chimeric animal that could occur due ...
<p>A: normalized melting curves; B: normalized difference curves. HRMA identified mutated R882H with...
<p>Grey lines represented wild-type <i>SRSF2</i>; green and blue lines were validated as P95H mutati...
<p>HRM can efficiently identify single gene mutation containing F1 from pooled guide injections.</p
Detecting NPM1 gene mutations using the E-ice-COLD-PCR assay and generating the data into HRM differ...
<p>A&B) General depiction of HRM analysis. A homozygous wild-type sample (double blue lines in A) wi...
a<p>[Number of drug-resistant isolates with mutations]/[number of drug-resistant isolates with mutat...
Wild-type (pcDNA3.1-EGFRwild-type) and mutant (pcDNA3.1-EGFRL858R/T790M) EGFR expression plasmids we...
<p><i>BRAF</i> mutation status determined by HRM using DNA treated with BSA or purified using the Nu...
<p>Melting curves (A) and difference plots (B) of wild-type (blue) and serial dilutions of a <i>CALR...
Somatic mutations of the spliceosome machinery have been recently identified by whole genome analysi...
High Resolution Melting Analysis (HRMA) is becoming the preferred method for mutation detection. How...
Conventional mutation analysis requires a separation step and include single-strand conformational p...