Enhancement of chondrogenic differentiation of hMSCs by ZNF449.
- Keita Okada (2220235)
- Atsushi Fukai (266981)
- Daisuke Mori (458964)
- Yoko Hosaka (2220232)
- Fumiko Yano (266988)
- Ung-il Chung (34003)
- Hiroshi Kawaguchi (33997)
- Sakae Tanaka (35403)
- Toshiyuki Ikeda (35392)
- Taku Saito (35393)
Publication date
December 2014
DOIAbstract
<p>(A) mRNA levels of <i>ZNF449, SOX9, SOX6 and COL2A1</i> during chondrogenic differentiation of hMSCs. Data are expressed as means (bars) ± SDs (error bars) for three wells/group. *<i>P</i><0.05, <sup>#</sup><i>P</i><0.01 versus 0 d. (B) mRNA levels of <i>SOX9, SOX6 and COL2A1</i> during chondrogenic differentiation of hMSCs transduced with GFP or ZNF449 by adenovirus. Adenoviral transduction was performed 2 days before the differentiation. Data are expressed as means (bars) ± SDs (error bars) for three wells/group. *<i>P</i><0.05 versus GFP. (C) Protein levels of the transduced ZNF449 (HA) and Actin during the differentiation of hMSC.</p
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