<p>(A) mRNA level of <i>Zfp449</i> in mouse tissues. Data are expressed as means (bars) ± SDs (error bars) for three wells/group. (B) Immunofluorescence of Zfp449 in limb cartilage of mouse embryo. Inset boxes in the top panel indicate the regions of the bottom three rows representing periarticular (Per) zone, proliferative (Pro) zone, and hypertrophic (Hyp) zone. Scale bars, 100 µm (top), 20 µm (bottom). (C) Immunofluorescence of Zfp449 in articular cartilage of 8-week-old mouse knee joint. Inset box in middle panel indicates the regions of the bottom three rows. Scale bars, 100 µm (top and middle), 10 µm (bottom).</p
<p>(A) Structure of ZFHX2 and related proteins. ZFHX2 is a protein of 2562 amino acids containing 18...
<p>(A) Quantification of the chondrocyte number per cartilage area in femur and tibia sections from ...
<p>Gene expression was determined by qPCR. Graphs show gene expression for (A). <i>MGP</i>, (B). <i>...
<p>(A) Safranin-O staining and immunofluorescence of Sox9, Sox6, Col2a1 and Zfp449 in proximal tibia...
<p>(A) Relative <i>ZNF354C</i> mRNA levels in the kidney and brain in mice, quantified by real-time ...
<p>(A) Schematic representation of the <i>Zfp449</i> locus and engineering of a <i>Zfp449</i> null a...
<p>A–B): <i>Slc39a1-14</i> mRNA expression in C2C12 cells and mouse quadriceps, respectively. Error ...
<p>(<b>A</b>) Western blots of total protein extracts from different mouse tissues. The blot of the ...
<p>Relative gene expression (mean ± SEM) of a subset of BMP agonists (top row), BMP functional antag...
<p><i>(A)</i> Immunofluorescent analysis for ATF4 in tibial epiphyseal cryosections from 2 week wild...
<p>Relative gene expression (mean ± SEM) of a subset of BMP agonists (top row), BMP functional antag...
Characterisation of mice lacking either Zfp36l1 or Zfp36l2 (referred to as Zfp36L1-P or Zfp36L2-P mi...
<p>Detection of GFP expression in Dmp1-GFP derived histological sections (A–D). A specific GFP signa...
<p>Serial transverse sections of 10-d-old tibiae were collected for quantitative RT-PCR analyses. A ...
<p>Column headings represent; WT = wild type mice, HYP = X-linked hypophosphatemic rickets mice,...
<p>(A) Structure of ZFHX2 and related proteins. ZFHX2 is a protein of 2562 amino acids containing 18...
<p>(A) Quantification of the chondrocyte number per cartilage area in femur and tibia sections from ...
<p>Gene expression was determined by qPCR. Graphs show gene expression for (A). <i>MGP</i>, (B). <i>...
<p>(A) Safranin-O staining and immunofluorescence of Sox9, Sox6, Col2a1 and Zfp449 in proximal tibia...
<p>(A) Relative <i>ZNF354C</i> mRNA levels in the kidney and brain in mice, quantified by real-time ...
<p>(A) Schematic representation of the <i>Zfp449</i> locus and engineering of a <i>Zfp449</i> null a...
<p>A–B): <i>Slc39a1-14</i> mRNA expression in C2C12 cells and mouse quadriceps, respectively. Error ...
<p>(<b>A</b>) Western blots of total protein extracts from different mouse tissues. The blot of the ...
<p>Relative gene expression (mean ± SEM) of a subset of BMP agonists (top row), BMP functional antag...
<p><i>(A)</i> Immunofluorescent analysis for ATF4 in tibial epiphyseal cryosections from 2 week wild...
<p>Relative gene expression (mean ± SEM) of a subset of BMP agonists (top row), BMP functional antag...
Characterisation of mice lacking either Zfp36l1 or Zfp36l2 (referred to as Zfp36L1-P or Zfp36L2-P mi...
<p>Detection of GFP expression in Dmp1-GFP derived histological sections (A–D). A specific GFP signa...
<p>Serial transverse sections of 10-d-old tibiae were collected for quantitative RT-PCR analyses. A ...
<p>Column headings represent; WT = wild type mice, HYP = X-linked hypophosphatemic rickets mice,...
<p>(A) Structure of ZFHX2 and related proteins. ZFHX2 is a protein of 2562 amino acids containing 18...
<p>(A) Quantification of the chondrocyte number per cartilage area in femur and tibia sections from ...
<p>Gene expression was determined by qPCR. Graphs show gene expression for (A). <i>MGP</i>, (B). <i>...