miR-193a repress E2F6 and c-KIT.
- Frank H. C. Cheng (697928)
- Baltazar D. Aguda (219379)
- Je-Chiang Tsai (697929)
- Marek Kochańczyk (30349)
- Jora M. J. Lin (697930)
- Gary C. W. Chen (697931)
- Hung-Cheng Lai (151505)
- Kenneth P. Nephew (212536)
- Tzy-Wei Hwang (697932)
- Michael W. Y. Chan (212530)
Publication date
December 2014
DOIAbstract
<p>(A) Schematic diagram of c-KIT and E2F6 mRNA showing predicted miR-193a binding site at their 3′UTR. The detailed binding sequences (MREs) of these sites are also shown along with miRNA sequence alignments. (B) qPCR analysis of miR-193a, c-KIT and E2F6 in A2780 ovarian cancer cells. Overexpression of miR-193a in A2780 cells leads to down-regulation of c-KIT and E2F6 mRNAs.</p
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