<p>Variants were judged as known by their being listed in dbSNP. Variant counts for those unique to both samples are also shown. The lowest frequency variant detected for each variant type (SNV, insertion, deletion, and substitution, respectively) in each sample was 0.88%, 3.7%, 10.07%, and 4.57% in the tumor, and 7.41%, 3.01%, 10.07%, 2.78% in the node.</p><p>Known and novel variant counts at a read-depth of ≥100 that overlapped genes and their flanking regions.</p
<p>Box plot of average read frequencies of transposon insertions in tumors and tail controls. Dots s...
<p>The match between the test genome and the reference genome sequence was scored at each bp for all...
We conducted the largest investigation of predisposition variants in cancer to date, discovering 853...
Whole exome sequencing (WES) of matched tumor-normal pairs in rare tumors has the potential to ident...
International audienceSingle-nucleotide variants (SNVs) are the most frequent genetic changes found ...
Tumor analyses commonly employ a correction with a matched normal (MN), a sample from healthy tissue...
<p>Five cases with matched tumor—blood samples are shown. Annotations in black letters are given for...
<p><b>A</b>–<b>B</b>. Comparison of the variant allelic frequency of mutations detected using whole ...
<p>3 <i>CRP</i> SNPs (rs7553007, rs1205, and rs3093077) and 21 additional SNPs of 141 tumor/normal s...
We examined 55 technical sequencing replicates of Glioblastoma multiforme (GBM) tumors from The Canc...
<p>SNPs are shown in black/grey, insertions in red, deletions in blue, and complex variants in orang...
A. Distribution of all SNVs (n = 11,350). B. Distribution and consequences of novel SNVs (n = 2,598)...
Variant genes found in 3 or more patients for ACC, N = 27 (A), GIST, N = 22 (B), and NEN, N = 24 (C)...
<p>Summary of all variants identified in this study, the majority of which were found in primary tum...
Quantification of tumor‐specific variants (TSVs) in cell‐free DNA is rapidly evolving as a prognosti...
<p>Box plot of average read frequencies of transposon insertions in tumors and tail controls. Dots s...
<p>The match between the test genome and the reference genome sequence was scored at each bp for all...
We conducted the largest investigation of predisposition variants in cancer to date, discovering 853...
Whole exome sequencing (WES) of matched tumor-normal pairs in rare tumors has the potential to ident...
International audienceSingle-nucleotide variants (SNVs) are the most frequent genetic changes found ...
Tumor analyses commonly employ a correction with a matched normal (MN), a sample from healthy tissue...
<p>Five cases with matched tumor—blood samples are shown. Annotations in black letters are given for...
<p><b>A</b>–<b>B</b>. Comparison of the variant allelic frequency of mutations detected using whole ...
<p>3 <i>CRP</i> SNPs (rs7553007, rs1205, and rs3093077) and 21 additional SNPs of 141 tumor/normal s...
We examined 55 technical sequencing replicates of Glioblastoma multiforme (GBM) tumors from The Canc...
<p>SNPs are shown in black/grey, insertions in red, deletions in blue, and complex variants in orang...
A. Distribution of all SNVs (n = 11,350). B. Distribution and consequences of novel SNVs (n = 2,598)...
Variant genes found in 3 or more patients for ACC, N = 27 (A), GIST, N = 22 (B), and NEN, N = 24 (C)...
<p>Summary of all variants identified in this study, the majority of which were found in primary tum...
Quantification of tumor‐specific variants (TSVs) in cell‐free DNA is rapidly evolving as a prognosti...
<p>Box plot of average read frequencies of transposon insertions in tumors and tail controls. Dots s...
<p>The match between the test genome and the reference genome sequence was scored at each bp for all...
We conducted the largest investigation of predisposition variants in cancer to date, discovering 853...