IL-6 treatment upregulates viral gene expression in HCMV-infected GBM cells.

<p>At 5 weeks p.i. (or at 15 wks p.i. for AD169-infected 387 GSC) a subset of cells was treated with IL-6 for 24 hours before RNA extraction. A. Heatmap representation of viral gene expression in in TR or AD169-infected U87, T98G, and 387 GSC with or without IL-6 treatment B. HCMV pp71 was detected using Taqman in TR-infected T98G, TR-infected 387, and AD169-infected U87 cells. Mean values normalized to Rab14 are shown. Each sample was run in quadruplicate. *p<0.02 student T-test.