Organized Tertiary Lymphoid Structures in human Abdominal Aortic Aneurysm.

<p>(<b>A</b>) Representative immunohistochemical staining of CD3⁺ T cells (red), CD20⁺ B cells (green) and nuclei (DAPI, blue) performed on human AAA cross-sections (scale bar = 1 mm). (<b>B</b>) Flow cytometry analysis of the percentage of CD19⁺ B cells, total CD8⁺, CD4⁺and memory (CD4⁺CD45RO⁺) T cells in adventitia from AAAs (n = 9) or control aortas (n = 14). (<b>C</b>) Box plot showing the total IgG levels in conditioned medium prepared from adventitial tissues of AAAs (n = 14) and control aortas (n = 5) quantified by ELISA. *, p<0.05; **, p<0.01; ***, p<0.001.